The Biggie Bone is designed for dogs that love to chew and it stands up to the toughest chewers. Indentations on each end can be stuffed with peanut butter or other treats, so dogs will find it irrisistible. As with all SafeMade products, the Biggie Bone is made from extra durable food-grade silicone. It is safe to clean and sanitize in the dishwasher. This toy is even oven safe to 450-degree if you want to bake treats directly inside. The large Biggie Bone is appropriate for large dogs, that are moderate to tough chewers.